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Cialis is trade mark drug registered by Lilly ICOS (Eli Lilly and ICOS Corporation). It was approved in 21 Nov 2003 by FDA. Tadalafil is generic equivalant of cialis. Tadalafil is indicated for erectile dysfunction treatment (also called male impotence). Use of Tadalafil increases blood flow in penis muscels which cause erection. So far, tadalafil is being only used for erectile dysfunction.

How Tadalafil Works

As other erectile dysfunction medications (like sildenafil citrate and verdenafil) tadalafil is also PDE5 inhibitor. Blood flow increases in penile muscels during sexual stimulation and makes penis rigid or erected. In sexually stimulated time, nitric oxide released by central nervous system works with endothelial cells and secretes cGMP. cyclic GMP relaxes penile arteries and increase blood flow. PDE5 enzyme disturbs this events and cause less or no erection. Tadalafil inhibits PDE5 enzyme. cause relaxation arteries and corpus cavernosal muscles.

Thus tadalafil is very effective to boost mechanism of cGMP necessary for erection. Tadalafil is primerily prescribe to get and maintain erection.

Tadalafil Dose Cautions

Tadalafil is available in two strength 10mg 20mg. Take one tadalafil (dose as per guided by physician) tablet befor sexual intercourse.

Side Effects Of Tadalafil

No serious side effects have been reported so far. Some of the less harmful seide effects are...

1. Headache
2. Back pain
3. Myalgia
4. Dyspepsia
5. Nasal congestion
6. Flushing

Contradications with Tadalafil

Person must not take tadalafil if found to be in any conditions mentioned below

1. Cardio vasculer problems
2. Heart attack in past 90 days
3. Received stroke or congestive heart failure recently
4. High or low blood pressure
5. Angina (chest pain)
6. Suffering from hemophilia
7. Liver disease
8. kidney disease (or if you are on dialysis)
9. blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia
10. Retinitis pigmentosa (an inherited condition of the eye)
11. Physical deformity of the penis (such as Peyronie's disease)

Nitrate drug: One must avoid taking Tadalafil if administering nitrate drug also. Tadalafil is contraindicated with nitrate. Tadalafil increase hypotensive power of nitrate. So do not take tadalafil if you are administering nitrate drug or you may see decrease in blood pressure.

Rifampicin, phenobarbital, phenytoin, carbamazepine are some of the drugs which may cause low blood pressure if taken simultaneously.

Do not take tadalafil along with other erectile dysfunction medications as the effect is yet unknown.

• 10 Mg
• 20 Mg