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Pain of migraine headaches and cluster headaches is relived by Migranal. Migranal falls under ergot alkaloids family of medicines. The blood vessels in the head are constricted by this medicine. This relieves the widening of blood vessels, which is related to migraine headache pain.

How does Migranal work?
The blood vessels are temporarily constricted by Migranal around the skull and throughout the body. Migranal is more effective if it is taken at the first sign of a migraine attack.

If you miss a dose
Missing a dose of Migranal would not be a problem as it is used when required.

Symptoms of excess dose of Migranal
Overdose of Migranal may show symptoms such as confusion, convulsions, drowsiness, gangrene, itching, muscle pain, numbness in your fingers or toes, nausea, vomiting, weakness and possibly death.

Storage:
Migranal should be stored at room temperature away from moisture and heat.

Contraindication

Migranal reacts adversely during

  • Pregnancy
  • Poor blood flow to the extremities (hands and feet) (peripheral vascular insufficiency).
  • Narrowing of the blood vessels in the hands, causing numb and painful fingers (Raynaud's disease)
  • Known sensitivity or allergy to any ingredient
  • High blood pressure (hypertension)
  • Disease involving the blood vessels (vascular disease)
  • Cramping pain in the calf muscles brought on by exercise, due to narrowing of the arteries in the calves (intermittent claudication)
  • Coronary artery disease
  • Breastfeeding
  • Angina pectoris

What precautions should be taken?
Caution should be taken when using Migranal during

  • Severe inflammation of the liver, with a rapid onset and of short duration (acute hepatitis)
  • Infection of the blood or body tissues with pus-forming or other pathogenic organisms (sepsis)
  • Hyperthyroidism
  • Anaemia
  • Alcohol intake

Adverse effects of Migranal
Certain adverse effects observed with Migranal are:

  • Spasm of the arteries
  • Pins and needles (paraesthesia)
  • Numbness
  • Nausea
  • Muscle cramps
  • Joint pain (arthralgia)
  • Inflammation of the wall of a vein with a blood clot forming in the affected segment of vein (local thrombophlebitis)
  • Inadequate blood flow leading to low levels of oxygen in the tissues of the extremities (peripheral ischaemia), which may lead to gangrene
  • High blood pressure (hypertension)
  • Heart attack (myocardial infarction)
  • Dizziness
  • Difficulty in breathing (dyspnoea)
  • Diarrhea
  • Cold extremities, e.g. hands and feet
  • Chest pain
  • Abdominal pain


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